abstract：OBJECTIVES:Scorpion venoms are a rich source of bioactive peptides with promising clinical value that may lead to the discovery and development of new drugs. The present study was designed to evaluate the in vitro antimicrobial activities of the venoms extracted from three medically important Saudi scorpions (Androcton...

journal_title：Journal of global antimicrobial resistance

authors： Al-Asmari AK,Alamri MA,Almasoudi AS,Abbasmanthiri R,Mahfoud M

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Vancomycin is the primary treatment for methicillin-resistant Staphylococcus aureus (MRSA). However, an increasing proportion of MRSA isolates with high minimum inhibitory concentrations (MICs) within the susceptible range (vancomycin 'MIC creep') is being observed. The aim of this study was to assess the va...

journal_title：Journal of global antimicrobial resistance

authors： Diaz R,Ramalheira E,Afreixo V,Gago B

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Multidrug-resistant (MDR) Enterobacter aerogenes strains are frequently associated with nosocomial infections and high mortality rates, representing a serious public health problem. The aim of this study was to present the draft genome sequence of a MDR KPC-2-producing E. aerogenes isolated from a perineal s...

journal_title：Journal of global antimicrobial resistance

authors： Moura Q,Fernandes MR,Cerdeira L,Nhambe LF,Ienne S,Souza TA,Lincopan N

更新日期：2017-09-01 00:00:00

abstract：:The genus Kluyvera comprises potential pathogens that can cause many infections. This study reports a Kluyvera intermedia strain (FOSA7093) from a pancreatic cyst specimen from a long-term hospitalised patient. Whole-genome sequencing (WGS) of the K. intermedia isolate was performed and the strain was reported as sens...

journal_title：Journal of global antimicrobial resistance

authors： Thele R,Gumpert H,Christensen LB,Worning P,Schønning K,Westh H,Hansen TA

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate the role of residue 238 in CTX-M-15 and CTX-M-15G238C mutant with respect to carbapenems and various β-lactamase inhibitors. METHODS:A CTX-M-15G238C laboratory mutant was generated by site-directed mutagenesis from CTX-M-15 enzyme by replacing glycine 238 with cysteine....

journal_title：Journal of global antimicrobial resistance

authors： Sabatini A,Brisdelli F,Celenza G,Marcoccia F,Colapietro M,Tavío MM,Piccirilli A,Amicosante G,Perilli M

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:Staphylococcus cohnii has become increasingly recognized as a potential pathogen of clinically significant nosocomial and farm animal infections. This study was designed to determine the genome of a multidrug-resistant S. cohnii subsp. urealyticus strain SNUDS-2 isolated from a farmed duck in Korea. METHODS...

journal_title：Journal of global antimicrobial resistance

authors： Han JE,Lee S,Jeong DG,Yoon SW,Kim DJ,Lee MS,Kim HK,Park SK,Kim JH,Park SC

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:The objective was to investigate how deficient of quorum sensing system (QS) affects minimal inhibitory concentrations (MICs) of Pseudomonas aeruginosa strains to ciprofloxacin (CIP) and levofloxacin (LEV) in vitro. METHODS:Collected the clinical Pseudomonas aeruginosa isolates. Screened the strains deficie...

journal_title：Journal of global antimicrobial resistance

authors： Gao Y,Duan J,Geng X,Zhang Z,Zhang R,Li X,Wang S,Kang J,Yin D,Song Y

更新日期：2017-09-01 00:00:00

abstract：:In the past few years, Europe has experienced an enormous influx of refugees and migrants owing to the ongoing civil war in Syria as well as conflicts, violence and instability in other Asian and African countries. Available data suggest that refugees carry a significant burden of multidrug-resistant (MDR) organisms, ...

journal_title：Journal of global antimicrobial resistance

authors： Maltezou HC,Theodoridou M,Daikos GL

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to examine the performance of the chromogenic β LACTA™ test for the rapid detection of expanded-spectrum cephalosporin (ESC) non-susceptibility among Enterobacteriaceae in a region endemic for potent β-lactamases. METHODS:The β LACTA™ test was applied prospectively on 235 consecuti...

journal_title：Journal of global antimicrobial resistance

authors： Vrioni G,Mamali V,Zarkotou O,Voulgari E,Dimitroulia E,Themeli-Digalaki K,Pournaras S,Tsakris A

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to determine the prevalence of nasal carriage of methicillin-resistant Staphylococcus aureus (MRSA) among healthcare workers (HCWs) compared with non-HCWs at Duhok city, Kurdistan Region, northern Iraq. METHODS:A total of 182 HCWs with different occupations and working in different...

journal_title：Journal of global antimicrobial resistance

authors： Hussein NR,Assafi MS,Ijaz T

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:With a worrisome surge of carbapenem-resistant bacterial isolates, the diagnostic arsenal has become in dire need of affordable and timely assays to detect the rapidly transmissible carbapenemases. Employing multiplex PCR as a reference method, the purpose of the present study was to compare the performance ...

journal_title：Journal of global antimicrobial resistance

authors： Madkour LA,Soliman MS,Hassan DM,Soliman NS,ElMahdy YA

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:Antibiotic resistance among Gram-negative pathogens isolated from ventilator-associated pneumonia (VAP) poses a grave threat in intensive care unit (ICU) patients. The aim of this study was to assess the prevalence of pathogens in ICU patients and their drug resistance profile. The prevalence of extended-spe...

journal_title：Journal of global antimicrobial resistance

authors： Gupta R,Malik A,Rizvi M,Ahmed M,Singh A

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:The present study aimed to screen for the presence of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae in wild boars and Barbary macaques in Béjaïa and Jijel, Algeria. METHODS:A total of 216 faecal samples collected between September 2014 and August 2015 were cultured on MacConkey agar supp...

journal_title：Journal of global antimicrobial resistance

authors： Bachiri T,Bakour S,Ladjouzi R,Thongpan L,Rolain JM,Touati A

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to validate the use of LML antimicrobial gradient strips for quantitative determination of carbapenem susceptibility in Enterobacteriaceae. METHODS:A total of 95 non-redundant Enterobacteriaceae strains isolated during 2012-2014 were used for this validation study. Initially, LML a...

journal_title：Journal of global antimicrobial resistance

authors： Sekar R,Srivani S,Lallitha S,Thenmozhi P,Devisri T,Amudhan M,Mythreyee M

更新日期：2017-03-01 00:00:00

abstract：:Acinetobacter baumannii coccobacilli are dangerous to patients in intensive care units because of their multidrug resistance to antibiotics, developed mainly in the past decade. This study aimed to examine whether there is a significant correlation between the number of Pro-Ala repeats in the CAP01997 protein, the Emr...

journal_title：Journal of global antimicrobial resistance

authors： Nowak-Zaleska A,Wieczór M,Czub J,Nierzwicki Ł,Kotłowski R,Mikucka A,Gospodarek E

更新日期：2016-12-01 00:00:00

abstract：:Enterococcus faecium was considered an important nosocomial pathogen that could incur a substantial health burden owing to its high drug resistance and its ability to adapt to the hospital niche. Here we presented the draft genome sequence of multidrug-resistant E. faecium XH877. The draft genome sequence was composed...

journal_title：Journal of global antimicrobial resistance

authors： Hua X,Sun L,Shi K,Yu Y

更新日期：2016-12-01 00:00:00

abstract：:This study identified a novel integrative and conjugative element (ICESsD9) carrying erm(B) and tet(O) resistance determinants in Streptococcus suis D9 and determined its prevalence in clinical isolates. Comparative genome analysis was performed using Mauve and Artemis Comparison Tool visualisation programs. Inverse P...

journal_title：Journal of global antimicrobial resistance

authors： Huang K,Song Y,Zhang Q,Zhang A,Jin M

更新日期：2016-12-01 00:00:00

abstract：:Klebsiella pneumoniae carrying blaCTX-M-15 have been widely disseminated in hospital settings. In this regard, most clinically important strains belong to clonal complex 28 (CC258), which includes sequence type 340 (ST340). In this study, we present the draft genome sequence of a CTX-M-15-producing ST340 K. pneumoniae...

journal_title：Journal of global antimicrobial resistance

authors： Cerdeira L,Silva KC,Fernandes MR,Ienne S,de Souza TA,de Oliveira Garcia D,Moreno AM,Lincopan N

更新日期：2016-12-01 00:00:00

abstract：:The aim of this work was to analyse extended-spectrum β-lactamase (ESBL)-producing Escherichia coli strains isolated from outpatients with signs of cystitis in Hospital Universitário de Brasília (Brasília, Brazil) during the period July 2013 to April 2014. E. coli isolated from urine culture were identified and their ...

journal_title：Journal of global antimicrobial resistance

authors： Gonçalves LF,de Oliveira Martins-Júnior P,de Melo ABF,da Silva RCRM,de Paulo Martins V,Pitondo-Silva A,de Campos TA

更新日期：2016-09-01 00:00:00

abstract：:Antibiotic resistance genes are rapidly spread between pathogens and the normal flora, with plasmids playing an important role in their circulation. This study aimed to investigate antibiotic resistance plasmids in the gut microbiome of hospitalised patients. Stool samples were collected from seven inpatients at Sirir...

journal_title：Journal of global antimicrobial resistance

authors： Jitwasinkul T,Suriyaphol P,Tangphatsornruang S,Hansen MA,Hansen LH,Sørensen SJ,Permpikul C,Rongrungruang Y,Tribuddharat C

更新日期：2016-09-01 00:00:00

abstract：:The emergence of drug-resistant tuberculosis (TB) is a major public health threat. However, little is known about the predictors of death in drug-resistant TB in Malaysia. This study aimed to determine the predictors of death in drug-resistant TB patients, including multidrug-resistant TB (MDR-TB), in Kuala Lumpur, Ma...

journal_title：Journal of global antimicrobial resistance

authors： Mohd Shariff N,Shah SA,Kamaludin F

更新日期：2016-09-01 00:00:00

abstract：:Antimicrobial resistance severely limits the therapeutic options for many clinically important bacteria. In Gram-negative bacteria, multidrug resistance is commonly facilitated by plasmids that have the ability to accumulate and transfer refractory genes amongst bacterial populations. The aim of this study was to isol...

journal_title：Journal of global antimicrobial resistance

authors： Oyedemi BO,Shinde V,Shinde K,Kakalou D,Stapleton PD,Gibbons S

更新日期：2016-06-01 00:00:00

abstract：:Haemophilus influenzae is an important human pathogen usually susceptible to quinolones. Here we report the emergence of high-level ciprofloxacin-monoresistant H. influenzae in the Region of Southern Denmark. Four isolates were collected for phenotypic and molecular characterisation using whole-genome sequencing (WGS)...

journal_title：Journal of global antimicrobial resistance

authors： Fuursted K,Hartmeyer GN,Stegger M,Andersen PS,Justesen US

更新日期：2016-06-01 00:00:00

abstract：:This study aimed to evaluate the clinical outcomes of vancomycin-resistant enterococcal bloodstream infections (VRE BSI) caused by Enterococcus gallinarum or Enterococcus casseliflavus. Variables associated with treatment failure were determined and treatment options were compared. This was a national retrospective st...

journal_title：Journal of global antimicrobial resistance

authors： Britt NS,Potter EM

更新日期：2016-06-01 00:00:00

abstract：:Various molecular methods have been developed to rapidly detect clarithromycin (CLR) resistance in Helicobacter pylori isolates in clinical specimens. All of these assays for detecting CLR resistance in H. pylori are based on detection of mutations in the 23S rRNA gene. In this article, we summarise current knowledge ...

journal_title：Journal of global antimicrobial resistance

authors： Xuan SH,Wu LP,Zhou YG,Xiao MB

更新日期：2016-03-01 00:00:00

abstract：:Mycobacterium tuberculosis is naturally resistant to clarithromycin (CLR). The genes Rv3197A (whiB7) and Rv1988 (ermMT) have been shown to be involved in the resistant phenotype. In this study, a CLR-susceptible M. tuberculosis clinical strain was identified, designated as DS3214, and the nucleotide sequences and expr...

journal_title：Journal of global antimicrobial resistance

authors： Warit S,Phunpruch S,Jityam C,Jaitrong S,Billamas P,Chaiprasert A,Palittapongarnpim P,Prammananan T

更新日期：2015-12-01 00:00:00

abstract：:In this study, 26 clinical isolates of Mycobacterium abscessus complex strains were characterised using available identification algorithms for the three species (M. abscessus, M. massiliense and M. bolletii) and the genotypic characteristics of clarithromycin (CLR) resistance were determined. Strains were identified ...

journal_title：Journal of global antimicrobial resistance

authors： Ramírez A,de Waard JH,Araque M

更新日期：2015-09-01 00:00:00

abstract：:Acquisition of carbapenemase-producing Klebsiella pneumoniae (CP-Kp) strains poses a major threat to critically ill patients. The objectives of this study were to describe the epidemiology of CP-Kp isolates as well as the clinical outcome associated with the corresponding infections and to identify risk factors for mo...

journal_title：Journal of global antimicrobial resistance

authors： Katsiari M,Panagiota G,Likousi S,Roussou Z,Polemis M,Alkiviadis Vatopoulos C,Evangelia Platsouka D,Maguina A

更新日期：2015-06-01 00:00:00

abstract：:The objective of this review was to describe the 'state of the art' of Plasmodium falciparum resistance to the main antimalarial drugs. A brief note on Plasmodium vivax is also included. Resistance of P. falciparum to the various antimalarials has a long history of hits and misses. During the last 60 years, the pace a...

journal_title：Journal of global antimicrobial resistance

authors： Severini C,Menegon M

更新日期：2015-06-01 00:00:00

abstract：:Hospitals in Hong Kong, like many hospitals in the world, are constantly challenged by the increasing rate of non-susceptible and multidrug-resistant organisms (MDROs). Accurate and timely surveillance is essential for effective control. The Hospital Authority of Hong Kong has developed a comprehensive antimicrobial s...

journal_title：Journal of global antimicrobial resistance

authors： Lai CK,Chuang WM,Kong MY,Siu HK,Tsang DN

更新日期：2014-12-01 00:00:00

abstract：:Uropathogenic Escherichia coli (UPEC) is the most frequent cause of urinary tract infection (UTI). Virulence factors (VFs) of UPEC in children are not well known. Circulating antibiotic resistance mechanisms in the community are increasing. In this study, the aetiological agents of UTI and antibiotic resistance mechan...

journal_title：Journal of global antimicrobial resistance

authors： Robino L,García-Fulgueiras V,Araujo L,Algorta G,Pírez MC,Vignoli R

更新日期：2014-12-01 00:00:00

abstract：:Acinetobacter calcoaceticus-baumannii complex is a common cause of hospital-acquired infections (HAIs) globally, remarkable for its high rate of antibiotic resistance, including to carbapenems. There are few data on the resistance of A. baumannii in Vietnam, which are essential for developing evidence-based treatment ...

journal_title：Journal of global antimicrobial resistance

authors： Van TD,Dinh QD,Vu PD,Nguyen TV,Pham CV,Dao TT,Phung CD,Hoang HT,Tang NT,Do NT,Nguyen KV,Wertheim H

更新日期：2014-12-01 00:00:00

abstract：:The rapid development of antimicrobial resistance among micro-organisms is a serious public health concern. Moreover, the dissemination of antibiotic-resistant bacteria makes this issue a global problem, and Asia is no exception. For example, since New Delhi metallo-β-lactamase (NDM)-producing Enterobacteriaceae were ...

journal_title：Journal of global antimicrobial resistance

authors： Lai CC,Lee K,Xiao Y,Ahmad N,Veeraraghavan B,Thamlikitkul V,Tambyah PA,Nelwan RH,Shibl AM,Wu JJ,Seto WH,Hsueh PR

更新日期：2014-09-01 00:00:00

abstract：:β-Lactams are a commonly used class of bactericidal antibiotics. The number of β-lactam-resistant pathogens is constantly increasing in hospitals around the world. Interestingly, most of the β-lactam-resistant bacteria carry mobile genetic elements, such as conjugative plasmids, that render the pathogen resistant. The...

journal_title：Journal of global antimicrobial resistance

authors： Ojala V,Mattila S,Hoikkala V,Bamford JK,Jalasvuori M

更新日期：2014-09-01 00:00:00

abstract：:Staphylococcus pseudintermedius is a frequent pathogen in dogs. The emergence of meticillin-resistant S. pseudintermedius (MRSP), which is concomitantly resistant to nearly all veterinary licensed antibiotics used for systemic treatment in dogs, is a major problem for veterinarians. In France, 16.9% (41/243) of the S....

journal_title：Journal of global antimicrobial resistance

authors： Haenni M,de Moraes NA,Châtre P,Médaille C,Moodley A,Madec JY

更新日期：2014-06-01 00:00:00

abstract：:Selection of resistant pathogens by antimicrobial use is probably the most important cause of antimicrobial resistance. Antimicrobial stewardship (AMS) refers to a multifaceted approach to optimise prescribing. The benefits of AMS programmes have been widely demonstrated in terms of reductions in antimicrobial use, mo...

journal_title：Journal of global antimicrobial resistance

authors： Levy Hara G

更新日期：2014-03-01 00:00:00

abstract：:The two closely related mycobacteria, Mycobacterium intracellulare and Mycobacterium chimaera, exhibit a more than two-fold difference in their in vitro susceptibility to sulfonamides. Sulfonamides are antibiotics targeting the 6-hydroxymethyl-7,8-dihydropteroate synthase (DHPS) enzyme involved in the folate synthesis...

journal_title：Journal of global antimicrobial resistance

authors： Gotthard G,Muhammed Ameen S,Drancourt M,Chabriere E

更新日期：2013-12-01 00:00:00

abstract：:Bacterial resistance is undoubtedly recognised as a major medical challenge in most healthcare systems. Resistance-determining genes, mostly in combination, and multidrug-resistant (MDR) pathogens are spreading with unprecedented speed. Well known resistance carriers with high clinical impact include the Gram-positive...

journal_title：Journal of global antimicrobial resistance

authors： Theuretzbacher U

更新日期：2013-06-01 00:00:00

abstract：:Although molecular methods can now provide fast identification and the antibiotic susceptibility profile of infecting pathogens, these techniques are not affordable by a large majority of clinical laboratories in developing countries and can be considered excessive for simple, community-acquired infections. Most antib...

journal_title：Journal of global antimicrobial resistance

authors： Amábile-Cuevas CF

更新日期：2013-03-01 00:00:00